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Revman 5 3 free downloads4/10/2023 Although meta-analysis is applied in many types of research, the bulk of published meta-analyses are in the domain of therapeutic and – albeit to a lesser extent – observational etiologic studies. ![]() As the quantitative part of a systematic review, the merit of meta-analysis over qualitative approaches lies in the formal and reproducible investigation of heterogeneity, small study effects, and other data trends. However, time has taught – both opponents and proponents – that things are not black and white meta-analysis, executed with care, has become an important and influential cornerstone of scientific medicine. Meta-analysis has been characterized in various ways, from "making order of scientific chaos" to "mega-silliness", and has been subject of many debates.
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